Must read this article ( Activity of Protein Kinase RIPK3 Determine Whether Cells Die by Necroptosis or Apoptosis) link to the article in pdf file is below. Must explain what’s going on in the article as if you’re telling a story. Please follow instructions on what to include and add.

Link of the article to present:

https://www.sciencemag.org/content/343/6177/1357.full.pdf

Rubric is attached for guidance and what is expected.

***The Anatomy of a Scientific Presentation

The title…
The first couple of sentences (and possibly the title) should catch the audience’s interest. You will not always have a captive audience. Consider having two titles: the lay catchy one and the scientific one.

The Background…
What is needed for the audience to understand why this work should be done? What is the basic question? Most comprehensive review articles are boring (except to the person writing the intro to a thesis). Don’t make your introduction sound like one. Does the audience really have to know the gene structure and molecular weight of all proteins related to your work? Focus on the information that is pertinent for your presentation.

The Hypothesis and Objectives…
You should state the basic question being asked in the paper (or in your own work) in scientific terms, and then in lay terms. Think how you can make it of interest to the audience. Why is this question important to ask? Why did the author bother doing these experiments? State the MAJOR scientific objectives of the paper (or your work)

The Experimental Methods…
This can be a great learning experience for all so don’t bore the audience with details. Don’t describe all of the methods near the beginning of your presentation. You have to understand the methods and the instrumentation used but describe them as you go providing the audience with information about how the technique (and/or instrument) works, what it can tell you, and how sensitive it is.

The Results…
Focus on the IMPORTANT experiments. Do not attempt to present every figure or table in the article.
– What is the question being asked? Why was the experiment done? How was it addressed experimentally? Why?
– Explain how the data are being represented. For example: what do the axes of a graph mean? Draw attention to the most important data in a figure or table.
– Describe what the experiment tells you, highlighting trends and or specific points you wish to make. How do the results compare to what you might have predicted or expected?
– Continue to the next slide. Why was the next experiment done, what results were expected, what was observed…and so on.
Each slide in the results is a mini seminar. Ideally, give it an introduction before putting it up. Summarize the results in simple terms and/or lay terms.

The Conclusion(s)…
Summarize the paper or your work in simple and/or lay terms. Explain how the results relate to the working hypothesis and the “big picture”. Your final remarks and the take home message is what the audience will remember – work on them. Don’t feel as if you have to defend the results or the conclusions. Be critical if you have concerns
. What is your opinion? If you feel the work was not well conceived, or the experiments were not well controlled, or the article was poorly written, say so

Last, critique the scientific paper by providing reasons and explanation

Also, at the end of article, there is a link to supplemental data, please use some of the information there.

Thank you.