In your own words (please do not copy the wording of the article), use the article Sickle Hemoglobin (Hb S) Allele and Sickle Cell Disease : A HuGE Review to answer the questions below:
- What are the at-risk genotypes associated with Hb S? Use this article or Figure 3.9 to help you. (0.5 points)
- What is the mode of inheritance? (0.25 points)
- Briefly list the symptoms individuals who have 2 copies, or 1 copy of the Hb S variant experience? (0.75 points)
- What is the difference in phenotype between normal carrier, diseased individuals? (0.5 points)
- Why has the frequency of individuals of African Mediterranean ancestries maintained the sickle cell trait? (0.5 points)
- Create a punnett square using 2 ca