Why is respiration slower on glutamate than on succinate

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August 4, 2017
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Why is respiration slower on glutamate than on succinate

Why is respiration slower on glutamate than on succinate?
A. electron transport from glutamate stores more energy per oxygen atom than electron transport from succinate
B. electron transport from glutamate stores less energy per oxygen atom than electron transport from succinate
C. the ADP:O ratio for glutamate supported respiration is 2
D. the RCR for glutamate supported respiration is higher than the RCR for succinate supported respiration
E. the gradient loses energy at a faster rate on glutamate than on succinate

Suppose you have mitochondria that are respiring on succinate and there is no ADP in the chamber. Now add a substrate that completely inhibits ATP synthase (stops oxidative phosphorylation). What should happen to the rate of oxygen consumption?
A. it should speed up
B. it should slow down
C. it should stay the same

This one requires that you think about what limits the respiration rates in states IV, III, and in uncoupled mitochondria. Which of the following situations should produce the fastest rate of respiration? Let the substrate be the same in each case.
A. respiration on a substrate only
B. respiration on a substrate plus ADP
C. respiration on a substrate plus an uncoupling agent

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