Why d-glucose would be less likely than other aldoses

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Why d-glucose would be less likely than other aldoses

In an aqueous solution, virtually all D-Glucose molecules (>99%) are in pyranose form. Other aldoses have a greater proportion of molecules in the open chain form. D-Glucose may have evolved to be the predominant metabolic fuel because it is less likely than its isomers to react with and damage cellular proteins. Explain why D-Glucose would be less likely than other aldoses to react with amino groups of proteins.

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