Which is not true about humulin

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Which is not true about humulin

Which is not true about Humulin? 
a. it was first recombinant DNA to be approved by the FDA
b. it is causes more adverse reactions in human as compared to insulin from cows… 
c. it was the first genetically engineered pharmaceutical product 
d. it is mass produced by Eli Lilly pharmaceutical company 

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