What is mutation rate, Tay Sachs, an autosomal recessive

Describe pathophysiological processes
August 4, 2017
Solution-Heat of vaporization and latent heat of
August 4, 2017
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What is mutation rate, Tay Sachs, an autosomal recessive

Tay Sachs, an autosomal recessive genetic disease in humans has a frequency (q2, assuming random mating) of about 2×10-6; assuming random mating, therefore, the frequency of the Tay-Sachs allele, q is about 1.4×10-3 . Tay-Sachs sufferers usually die within two years (s=0.9). If this disease is at mutation-selection balance, What is mutation rate. Please show work and formulas .

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